Cefadroxil monohydrate,66592-87-8

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产品名称：Cefadroxil monohydrate

产品别名：头孢羟氨苄

英文别名：Cefadroxil monohydrate

靶点：Antibacterial

CAS：66592-87-8

纯度：≥97%

外观：白色或类白色固体

保存方法：Store at -20° C

描述：

Cefadroxil is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections.

溶解性：DMSO ：7 mg/mL (18.35 mM)
Water ：1 mg/mL (2.62 mM)

体外研究：

Cefadroxil is a first generation aminocephalosporin with good patient compliance, a long-acting therapeutic effect, high solubility and relatively broad spectrum of anti-bacterial activity. Cefadroxil is also a substrate of the intestinal peptide transporter PepT1, which is primarily responsible for the drug’s uptake across the apical membrane of small intestine.

体内研究：Cefadroxil has low plasma protein binding (~20%) and good oral bioavailability of at least 90%. Renal excretion is the primary route of elimination, with more than 90% of the orally administered drug being excreted unchanged in urine over 24 hours.

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