Tedizolid Phosphate,856867-55-5

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产品名称：Tedizolid Phosphate

产品别名：磷酸特地唑胺

英文别名：TR-701FA

靶点：Antibacterial

CAS：856867-55-5

纯度：见爱必信官网

外观：见爱必信官网

保存方法：store at -20℃ for one year（Powder）； in DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months.

描述：Tedizolid is an oxazolidinone-class antibiotic. Tedizolid phosphate is a phosphate ester prodrug of the active compound tedizolid.

溶解性：体外:
DMSO 22mg/mL(48.85mM)
Water <1mg/mL
Ethanol <1mg/mL

体外研究：

Tedizolid (TR-700, formerly torezolid) is the active moiety of the prodrug tedizolid phosphate (TR-701), a next-generation oxazolidinone, with high potency against Gram-positive species, including methicillin-resistant Staphylococcus aureus (MRSA). Tedizolid is 4-fold more potent than linezolid against PRSP isolates in vitro.

体内研究：Tedizolid has excellent penetration into pulmonary epithelial lining fluid (ELF). Tedizolid phosphate administered to mice orally or intravenously is effective in vivo against systemic infection with PRSP isolates. Oral tedizolid phosphate is also effective in vivo against pneumonia induced with a PSSP strain.

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