Torezolid,856866-72-3

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YZ剂描述：

产品名称：Torezolid

产品别名：3-[3-氟-4-[6-(2-甲基-2H-四唑-5-基)-3-吡啶基]苯基]-5-(羟基甲基)-2-恶唑烷酮

英文别名：Tedizolid

靶点：Antibacterial

CAS：856866-72-3

纯度：98%

外观：见爱必信官网

保存方法：store at -20℃ for one year（Powder）； in DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months.

描述：Torezolid (TR-701; tedizolid) is a novel oxazolidinone for gram-positive infections.

溶解性：10 mM in DMSO

体外研究：

Tedizolid (0.25 μg/mL) inhibits all 28 clinical isolates of PRSP, and is 4-fold more potent than linezolid against PRSP.

体内研究：

For mice infected with PSSP type III, the survival rate is achieved with tedizolid phosphate at a minimum total daily dose of 10 mg/kg. Lungs of infected mice treated with tedizolid phosphate show less severe inflammation and edema, as indicated by the mean scores for inflammation and edema.

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