Flucloxacillin Sodium,1847-24-1

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产品名称：Flucloxacillin Sodium

产品别名：氟氯西林钠

英文别名：floxacillin sodium

靶点：Bacterial

CAS：1847-24-1

纯度：≥98%

外观：White to off-white powder

保存方法：Store at -20° C

描述：

Flucloxacillin sodium is the sodium salt of flucloxacillin, a penicillin antibiotic used to treat bacterial infections.

溶解性：DMSO ：95 mg/mL (199.64 mM)
Water ：95 mg/mL (199.64 mM)

体外研究：

The serum elimination half-life of flucloxacillin is 1.31-1.39 hours, and six hours after administration of a single 250 mg dose the serum concentration of flucloxacillin is 0.46 micrograms/mL. Oral flucloxacillin does not affect sweat electrolytes and is not a contraindication to sweat testing. Flucloxacillin has been reported to be metabolized in man to the penicilloic acid, the antibacterially active 5'-hydroxymethyl derivative and the penicilloic acid of the 5'-hydroxymethyl derivative. The metabolism of flucloxacillin in the rat is similar.

体内研究：

The serum elimination half-life of flucloxacillin is 1.31-1.39 hours, and six hours after administration of a single 250 mg dose the serum concentration of flucloxacillin is 0.46 micrograms/mL. Oral flucloxacillin does not affect sweat electrolytes and is not a contraindication to sweat testing. Flucloxacillin has been reported to be metabolized in man to the penicilloic acid, the antibacterially active 5'-hydroxymethyl derivative and the penicilloic acid of the 5'-hydroxymethyl derivative. The metabolism of flucloxacillin in the rat is similar.

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