Fluorometholone Acetate,3801-06-7

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产品名称：Fluorometholone Acetate

产品别名：氟米龙醋酸酯

英文别名：Fluorometholone Acetate

靶点：Glucocorticoid Receptor

CAS：3801-06-7

纯度：98%

外观：白色结晶性粉末

保存方法：Store at -20°C

描述：

Fluorometholone Acetate is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.

溶解性：DMSO ：84 mg/mL (200.71 mM)

体外研究：

Fluorometholone Acetate is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.

体内研究：Hourly topical administration of the drug suspension produces an average reduction of 46.8% in the polymorphonuclear leukocytes invading the corneal stroma. In the cornea, fluorometholone acetate appears to have a greater efficacy, as compared to fluorometholone alcohol, for reducing the number of leukocytes invading that tissue following an inflammatory stimulus. Animal toxicity studies of fluorometholone, including acute intraperitoneal LD50s in mice and rats, subacute oral toxicity in rats and dogs, and subacute topical ocular toxicity in rabbits have demonstrated the safety of this drug for human use.

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