Fructose 2,6-biphosphate sodium salt,84364-89-6

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产品名称：Fructose 2,6-biphosphate sodium salt

产品别名：见爱必信官网

英文别名：Fructose 2,6-biphosphate sodium salt

靶点：PFK-1, Fructose-1,6-Bisphosphatase

CAS：84364-89-6

纯度：见爱必信官网

外观：见爱必信官网

保存方法：store at -20℃ for one year（Powder）

描述：Fructose 2,6-biphosphate sodium salt is a potent stimulator of 6-Phosphofructo-1-kinase (PFK-1) and also inhibits Fructose-1,6-Bisphosphatase.

溶解性：In Vitro: H2O : 125 mg/mL (Need ultrasonic)

体外研究：

A concentration-dependent inhibition of fructose-1,6-Bisphosphatase by Fructose 2,6-bisphosphate is observed. Another characteristic of this inhibition is that it changes the saturation curve from hyperbolic to sigmoidal. This effect is clearly apparent at 25 pM Fructose 2,6-bisphosphate. It appears that the inhibitory actions of Fructose 2,6-bisphosphate and of AMP are synergistic. Indeed, at 10 pM fructose 1,6-bisphosphate, the addition of AMP alone causes a 35% inhibition but, it increases the inhibition by 1 pM Fructose 2,6-bisphosphate from 20% to 80%.

体内研究：A concentration-dependent inhibition of fructose-1,6-Bisphosphatase by Fructose 2,6-bisphosphate is observed. Another characteristic of this inhibition is that it changes the saturation curve from hyperbolic to sigmoidal. This effect is clearly apparent at 25 pM Fructose 2,6-bisphosphate. It appears that the inhibitory actions of Fructose 2,6-bisphosphate and of AMP are synergistic. Indeed, at 10 pM fructose 1,6-bisphosphate, the addition of AMP alone causes a 35% inhibition but, it increases the inhibition by 1 pM Fructose 2,6-bisphosphate from 20% to 80%.

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