公告提醒:爱必信所有产品和服务仅用于科学研究,不用于临床应用及其他用途提供产品和服务(也不为任何个人提供产品和服务)! YZ剂描述: 产品名称:KIN1148 产品别名:见爱必信官网 英文别名:KIN1148 靶点:IRF3 CAS:1428729-56-9 纯度:98% 外观:见爱必信官网 保存方法:store at -20℃ for one year(Powder) 描述:KIN1148, a small-molecule IRF3 agonist, is a novel influenza vaccine adjuvant found to enhance flu vaccine efficacy. 溶解性: In Vitro: DMSO : ≥ 100 mg/mL (276.67 mM) * "≥" means soluble, but saturation unknown. Preparing Stock Solutions ConcentrationSolventMass | 1 mg | 5 mg | 10 mg |
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1 mM | 2.7667 mL | 13.8336 mL | 27.6671 mL | 5 mM | 0.5533 mL | 2.7667 mL | 5.5334 mL | 10 mM | 0.2767 mL | 1.3834 mL | 2.7667 mL |
*请根据产品在不同溶剂中的溶解度,选择合适的溶剂配制储备液,并请注意储备液的保存方式和期限。 体外研究: KIN1148 induces the dose-dependent nuclear translocation of IRF3 in PH5CH8 cells and specific activation of IRF3- responsive promoters. KIN1148 also elicits greater induction of endogenous IRF3-dependent ISG54 and OASL expression by PH5CH8 cells. 体内研究:KIN1148 induces the dose-dependent nuclear translocation of IRF3 in PH5CH8 cells and specific activation of IRF3- responsive promoters. KIN1148 also elicits greater induction of endogenous IRF3-dependent ISG54 and OASL expression by PH5CH8 cells. 产品信息订购: 产品货号 | 产品名称 | 规格 | 价格 | 大包装及货期 | abs820750 | KIN1148 | 1mg | 1590 | 立即咨询 | 产品更多信息请进入爱必信网站咨询 |