AG-337;Nolatrexed dihydrochloride,152946-68-4

公告提醒：爱必信所有产品和服务仅用于科学研究，不用于临床应用及其他用途提供产品和服务（也不为任何个人提供产品和服务）!

YZ剂描述：

产品名称：AG-337;Nolatrexed dihydrochloride

产品别名：盐酸诺拉曲塞;二盐酸诺拉曲塞

英文别名：AG-337;Nolatrexed dihydrochloride

靶点：Thymidylate synthase

CAS：152946-68-4

纯度：98%

外观：Off-White to Pale Yellow Solid

保存方法：store at -20℃ for one year（Powder）； in DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months.

描述：

Nolatrexed Dihydrochloride is the dihydrochloride salt of nolatrexed, a water-soluble lipophilic quinazoline folate analog with antineoplastic activity. Nolatrexed occupies the folate binding site of thymidylate synthase, resulting in inhibition of thymidylate synthase activity and thymine nucleotide synthesis with subsequent inhibition of DNA replication, DNA damage, S-phase cell cycle arrest, and caspase-dependent apoptosis. This agent also exhibits radiosensitizing activity.

溶解性：DMSO > 10 mM

体外研究：

体内研究：

产品信息订购：

产品更多信息请进入爱必信网站咨询