Ebselen,60940-34-3_详细资料

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货号： abs816909 CAS号： 60940-34-3 供应商：爱必信(上海) 生物科技有限公司数量： 99 英文名：依布硒；SPI-1005； PZ-51； CCG-39161 保质期：见爱必信官网保存条件： store at -20℃ for one year（Powder）； in DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months. 规格： 5mg

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YZ剂描述：
产品名称：Ebselen
产品别名：依布硒
英文别名：SPI-1005;PZ-51;CCG-39161
靶点：COX
CAS：60940-34-3
纯度：＞98%
外观：Yellow to beige Crystalline Powder
保存方法：store at -20℃ for one year（Powder）； in DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months.
描述：
Ebselen is a organoselenium compound with anti-inflammatory, anti-oxidant and cytoprotective activity. Ebselen acts as a glutathione peroxidase mimetic and is thereby able to prevent cellular damage induced by reactive oxygen species (ROS). In addition, this agent inhibits the activity of a variety of enzymes including nitric oxide synthase (NOS), 5-lipoxygenase, cyclooxygenase, protein kinase C (PKC), NADPH oxidase and gastric H+/K+-ATPase. Furthermore, ebselen may be neuroprotective due to its ability to neutralize free radicals upon NMDA receptor activation thus, reducing lipoperoxidation mediated by glutamate-induced excitotoxicity.
溶解性：DMSO : 100mM
体外研究：
体内研究：
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