Dibutyl phthalate,84-74-2

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产品名称：Dibutyl phthalate

产品别名：邻苯二甲酸二丁酯

英文别名：Dibutyl phthalate

靶点：Others

CAS：84-74-2

纯度：0.99

外观：无色油状液体

保存方法：2-8°C

描述：

Dibutyl phthalate is a plasticizer used in most plastics and found in water, air, soil, plants and animals. It may have some adverse effects with long-term exposure.

溶解性：10 mM in DMSO

体外研究：

Dibutyl phthalate (0.001 µg/mL-1000 µg/mL) is detrimental to follicle growth and viability and results in significant dysregulation of cell cycle and apoptosis gene expression in a dose-specific manner. But MBP does not play a role in Dibutyl phthalate toxicity in follicles exposed in vitro.

体内研究：Dibutyl phthalate (200, 400, or 600 mg/kg/day) induces decrease mice weight, impairment of spermatogenesis, reduces serum follicle stimulating hormone and testosterone level, alters testicular LDH, increases LPO, and decreases the levels of enzymatic antioxidants with histopathological anomalies.Dibutyl phthalate (6.25, 12.5, 25, 50, 100 and 200 mg/kg) could cause some neurobehavioral adverse effects in mice.

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