Ancitabine hydrochloride,10212-25-6

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YZ剂描述：

产品名称：Ancitabine hydrochloride

产品别名：盐酸环胞苷

英文别名：Cyclocytidine hydrochloride;Cyclo-CMP hydrochloride;Cyclo-C

靶点：DNA/RNA Synthesis

CAS：10212-25-6

纯度：98%

外观：白色结晶性粉末

保存方法：store at -20℃ for one year（Powder）； in DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months.

描述：

Cyclocytidine is the prodrug of cytarabine, which is a pyrimidine nucleoside analog that inhibits the DNA synthesis and used mainly in the treatment of leukemia.

溶解性：DMSO : 10 mg/mL (38.22 mM)
Water : 40 mg/mL (152.9 mM)

体外研究：

Cyclocytidine HCl (Ancitabine) is the prodrug of cytarabine, which is structurally similar to human deoxycytidine to be incorporated into human DNA and then kills the cell. Cyclocytidine most affects rapidly dividing cells, which require DNA replication for mitosis. Cyclocytidine also inhibits both DNA and RNA polymerases and nucleotide reductase enzymes needed for DNA synthesis.

体内研究：Cyclocytidine is a potent immunosuppresant, antiviral and antitumor agent in animals and man, maximum inhibitor effects require the use of complex injection schedules. Cyclocytidine provides treatment for leukemia.

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