Rabbit anti-CASP3 Polyclonal Antibody,CASP3抗体

抗体描述：

产品名称：Rabbit anti-CASP3 Polyclonal Antibody

产品别名：A830040C14Rik; Apopain; CASP-3; CASP3; CASP3_HUMAN; Casp3a; Caspase 3; Caspase 3, apoptosis-related cysteine peptidase; Caspase 3, apoptosis-related cysteine protease; Caspase 3, apoptosis-related cysteine protease a; Caspase-3 subunit p12; CC3; CPP-32; C

特异性：CASP3 Antibody detects endogenous levels of total CASP3

来源：Rabbit

反应种属：Human Mouse Rat

克隆性：Polyclonal antibody

保存方法：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles

产品描述：This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.

用途范围：WB1:500-1:1000 IHC1:50-1:100

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