Rabbit anti-ABCG2(CD338) Polyclonal Antibody,ABCG2(CD338)抗体

抗体描述：

产品名称：Rabbit anti-ABCG2(CD338) Polyclonal Antibody

产品别名：ABC transporter; ABC15; ABCG 2; ABCG2; ABCG2_HUMAN; ABCP; ATP binding cassette sub family G (WHITE) member 2; ATP binding cassette transporter G2; ATP-binding cassette sub-family G member 2; BCRP; BCRP1; BMDP; Breast cancer resistance protein; CD338; CDw3

特异性：The antibody detects endogenous level of total ABCG2(CD338) protein.

来源：Rabbit

反应种属：Human, Mouse, Rat

克隆性：Polyclonal

保存方法：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles

产品描述：Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.

用途范围： WB 1:500-1:1000, ELISA(peptide) 1:20000-1:40000

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