Rabbit anti-CREB-BP Polyclonal Antibody,CREB-BP抗体

抗体描述：

产品名称：Rabbit anti-CREB-BP Polyclonal Antibody

产品别名：CBP; CBP_HUMAN; CREB binding protein; CREB-binding protein; Crebbp; Cyclic AMP responsive enhancer binding protein; KAT3A; RSTS; RTS; Rubinstein Taybi syndrome;

特异性：CREB-BP antibody detects endogenous levels of total CREB-BP.

来源：Rabbit

反应种属：Human, Mouse

克隆性：Polyclonal

保存方法：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles

产品描述：CBP a protein acetyltransferase that can transcriptionally activate histones. Acetylates the NCOA3 coactivator. Binds specifically to phosphorylated CREB1 and enhances its transcriptional activity toward cAMP-responsive genes. Methylation of the KIX domain by CARM1 blocks association with CREB, blocking CREB signaling, and activating the apoptotic response. Found in a complex containing NCOA2, NCOA3, IKKA, IKKB, and IKBKG. Probably part of a complex with HIF1A and EP300.

用途范围： WB: 1:500~1:3000, IHC: 1:50~1:200, IF/ICC: 1:100~1:500, ELISA(peptide) 1:20000-1:40000

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