CD34抗体,Anti-CD34抗体

产品名称：CD34抗体,Anti-CD34抗体做的更好 
中文名称：CD34抗体  
英文名称：Anti-CD34 
产品编号：byk-0646R 
产品规格：0.1ml/0.2ml
产品用途：科研实验
亚 型： IgG
贮 存： 贮存于-20℃
抗体的异质性。抗体的组成极为复杂，是由成千上万、多种多样的免疫球蛋白（Ig）分子所组成。这些Ig分子在形状、大小、结构以及氨基酸的组成和排列上，既相似，又有差别。由于有差别，它们的电泳活性就有很大的变化。
CD34抗体,Anti-CD34抗体做的更好 品说明：
The highly glycosylated 75-120 kD antigen CD34 is possibly an adhesion molecule with a putative role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. It could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. CD34 is thought to have a role in presenting carbohydrate ligands to selectins. The intracellular chain of the CD34 antigen is a site of phosphorylation by activated protein kinase C, suggesting a putative role in signal transduction. Two isoforms of CD34 have been reported to be generated by alternative splicing. CD34 is highly expressed on hematopoietic progenitors, as well as on endothelial cells, brain, and testis. Staining for CD34 has been used to measure angiogenesis, which reportedly predicts tumor recurrence.
保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 
CD34抗体,Anti-CD34抗体做的更好 关产品：
Anti-MICA(MHC class I polypeptide-related sequence A)  MHC I类链相关蛋白A抗体
Anti-Microsporidia  蜜蜂微孢子虫蛋白抗体
Anti-Midnolin isoform Protein 1  中脑核仁蛋白1抗体
Anti-Midnolin isoform Protein 2  中脑核仁蛋白2抗体
Anti-MK(Midkine)  中期因子/肝素结合生长因子抗体
Anti-MLCK(myosin light chain kinase)  肌球蛋白轻链激酶抗体
Anti-MIF (Macrophage Migration Inhibitory Factor)  巨噬细胞移动YZ因子抗体
Anti-MIP-1α (macrophage inflammatory protein 1α)  巨噬细胞炎症因子1α抗体
Anti-MIP-1β (macrophage inflammatory protein 1β)  巨噬细胞炎症因子1β 抗体
Anti-MIP4/CCL18(Macrophage inflammatory protein 4)  巨噬细胞炎症蛋白18抗体
抗体结构:
抗体是具有4条多肽链的对称结构，其中2条较长、相对分子量较大的相同的重链(H链)；2条较短、相对分子量较小的相同的轻链(L链)。链间由二硫键和非共价键联结形成一个由4条多肽链构成的单体分子。轻链有κ和λ两种，重链有μ、δ、γ、ε和α五种。 整个抗体分子可分为恒定区和可变区两部分。在给定的物种中，不同抗体分子的恒定区都具有相同的或几乎相同的氨基酸序列。可变区位于"Y"的两臂末端。在可变区内有一小部分氨基酸残基变化特别强烈，这些氨基酸的残基组成和排列顺序更易发生变异区域称高变区。高变区位于分子表面，多由17个氨基酸残基构成，少则只有2 ～ 3个。高变区氨基酸序列决定了该抗体结合抗原抗原的特异性。一个抗体分子上的两个抗原结合部位是相同的，位于两臂末端称抗原结合片段(antigen-binding fragment, Fab)。"Y"的柄部称结晶片段(crystalline fragment,FC)，糖结合在FC 上。