产品名称:CD48抗体,Anti-CD48/SLAMF2抗体优质推荐
中文名称:CD48抗体
英文名称:Anti-CD48/SLAMF2
产品编号:byk-2497R
产品规格:0.1ml/0.2ml
产品用途:科研实验
亚 型: IgG
贮 存: 贮存于-20℃
抗体的异质性。抗体的组成极为复杂,是由成千上万、多种多样的免疫球蛋白(Ig)分子所组成。这些Ig分子在形状、大小、结构以及氨基酸的组成和排列上,既相似,又有差别。由于有差别,它们的电泳活性就有很大的变化。
CD48抗体,Anti-CD48/SLAMF2抗体优质推荐 品说明:
CD48 is a glycosyl phophatidyl inositol (GPI) anchored cell surface protein also known as Blast1, HuLy m3, BCM1 (in mouse), and OX45 (in rat). CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibrolasts, epithelium and endothelium. CD48 is one of the markers for detecting the defects of GPI anchoring structure on patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2. The CD48 antigen is closely related to the activation antigen, Blast 1.
保存条件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
CD48抗体,Anti-CD48/SLAMF2抗体优质推荐 关产品:
Anti-MRP4/ABCC4抗体,多药耐药相关蛋白4抗体
Anti-MRP5/ABCC5 多药耐药相关蛋白5抗体
Anti-MrpL28 线粒体核糖体蛋白L28抗体
Anti-α-MSH/POMC α黑素细胞刺激素/阿黑皮素原抗体
Anti-MSH-2 抗体,错配修复蛋白2抗体
Anti-MLH1/hMLH 1抗体,错配修复蛋白1抗体
Anti-MSLN 抗体,间皮素抗体
Anti-MUCC/Mucin C抗体,胃粘液素抗体
Anti-MTHFR抗体,亚甲基四氢叶酸还原酶抗体
Anti-MTNR1A/MTR-1A抗体,褪黑素受体1A/松果体素受体1A抗体
抗体结构:
抗体是具有4条多肽链的对称结构,其中2条较长、相对分子量较大的相同的重链(H链);2条较短、相对分子量较小的相同的轻链(L链)。链间由二硫键和非共价键联结形成一个由4条多肽链构成的单体分子。轻链有κ和λ两种,重链有μ、δ、γ、ε和α五种。 整个抗体分子可分为恒定区和可变区两部分。在给定的物种中,不同抗体分子的恒定区都具有相同的或几乎相同的氨基酸序列。可变区位于"Y"的两臂末端。在可变区内有一小部分氨基酸残基变化特别强烈,这些氨基酸的残基组成和排列顺序更易发生变异区域称高变区。高变区位于分子表面,多由17个氨基酸残基构成,少则只有2 ~ 3个。高变区氨基酸序列决定了该抗体结合抗原抗原的特异性。一个抗体分子上的两个抗原结合部位是相同的,位于两臂末端称抗原结合片段(antigen-binding fragment, Fab)。"Y"的柄部称结晶片段(crystalline fragment,FC),糖结合在FC 上。