产品名称:转铁蛋白受体抗体,Anti-CD71抗体优质质量
中文名称:转铁蛋白受体抗体
英文名称:Anti-CD71/Transferrin receptor
产品编号:byk-1782R
产品规格:0.1ml/0.2ml
产品用途:科研实验
亚 型: IgG
贮 存: 贮存于-20℃
抗体的异质性。抗体的组成极为复杂,是由成千上万、多种多样的免疫球蛋白(Ig)分子所组成。这些Ig分子在形状、大小、结构以及氨基酸的组成和排列上,既相似,又有差别。由于有差别,它们的电泳活性就有很大的变化。
转铁蛋白受体抗体,Anti-CD71抗体优质质量 品说明:
Cellular uptake of iron occurs via receptor mediated endocytosis of ligand occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Useful in studies of dividing haematopoietic and tumour cell populations, and metabolic activity. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C terminal binding site. The antigen is present on most dividing cells, including normally cycling in vivo hematopoietic progenitor cells, mitogenically stimulated cells in vitro, some primary tumor cells and most proliferating cells in vitro.
保存条件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
转铁蛋白受体抗体,Anti-CD71抗体优质质量 关产品:
Anti-NCoR2 优质,核受体辅助YZ因子2抗体
Anti-NEP/MME优质,金属肽链内切酶抗体
Anti-NDRG1/Cap43优质,分化相关基因NDRG1抗体
Anti-NDRG2优质,抑癌基因NDRG2抗体
Anti-NDRG4抗体现货,抑癌基因NDRG4抗体
Anti-NCX1抗体,钠钙交换蛋白1抗体
Anti-NCX2/SLC8A2抗体,钠钙交换蛋白2抗体
Anti-Nebulin抗体,伴肌动蛋白抗体
Anti-NCX3抗体,钠钙交换蛋白3抗体
Anti-Mycoplasma Gallisepticum抗体,抗鸡毒支原体MG抗体
抗体结构:
抗体是具有4条多肽链的对称结构,其中2条较长、相对分子量较大的相同的重链(H链);2条较短、相对分子量较小的相同的轻链(L链)。链间由二硫键和非共价键联结形成一个由4条多肽链构成的单体分子。轻链有κ和λ两种,重链有μ、δ、γ、ε和α五种。 整个抗体分子可分为恒定区和可变区两部分。在给定的物种中,不同抗体分子的恒定区都具有相同的或几乎相同的氨基酸序列。可变区位于"Y"的两臂末端。在可变区内有一小部分氨基酸残基变化特别强烈,这些氨基酸的残基组成和排列顺序更易发生变异区域称高变区。高变区位于分子表面,多由17个氨基酸残基构成,少则只有2 ~ 3个。高变区氨基酸序列决定了该抗体结合抗原抗原的特异性。一个抗体分子上的两个抗原结合部位是相同的,位于两臂末端称抗原结合片段(antigen-binding fragment, Fab)。"Y"的柄部称结晶片段(crystalline fragment,FC),糖结合在FC 上。