Cd44 variant isoform 10-exon 16 antibody

Abnova产品货号： MAB12150
产品全称：   Cd44变体同种型10-外显子16 单克隆抗体
- 【Cd44 variant isoform 10-exon 16 (v10-e16) monoclonal antibody, clone RM1】
产品描述：针对小鼠Cd44变体同种型10-外显子16(v10-e16)产生大鼠单克隆抗体.
- 【Rat monoclonal antibody raised against mouse Cd44 variant isoform 10-exon 16 (v10-e16).】
基因名称及描述： 
Cd44 : CD44抗原-【CD44 antigen】
基因别名: AU023126|AW121933|AW146109|HERMES|Ly-24|Pgp-1
产品宿主： 大鼠 - 【Rat】
抗原种属： 小鼠 - 【Mouse】
适用实验样本种属： 小鼠 - 【Mouse】
承诺应用实验类型：Flow Cyt
产品组成： 暂无说明
注意事项： 癌症干细胞富集
癌症干细胞（CSC）已经被鉴定为许多肿瘤中不同群体的子集,并且可以通过其自我更新和分化成各种类型的癌细胞的能力来驱动癌症复发和转移. 因此,开发特异性和有效靶向CSC的疗法对于改善癌症患者的生存和生活质量是必要的,特别是对于患有转移性疾病的患者. 克隆RM1可用于细胞分选仪富集CSCs,并进一步应用于研究CSCs引起癌症复发和转移的机制,以开发针对CSC的新药.
- 【Cancer Stem Cell Enrichment
Cancer Stem Cells (CSCs) have been identified as a subset of distinct population in many tumors and can drive cancer relapse and metastasis with their abilities to self-renew and differentiate into various types of cancer cells. Development of therapies specifically and effectively targeting CSCs thus is necessary to improve the survival and quality of life for cancer patients, especially for patients with metastatic diseases.
Clone RM1 can be used for enrichment of CSCs with a cell sorter, and further be applied for studying mechanisms by which CSCs cause cancer relapse and metastasis to develop new drugs against CSCs.】