货号：
jlcR18592
保存条件：
-20 °
浓度：
1mg/ml
应用范围：
WB,ELISA等
适应物种：
人/动物/植物
抗体名：
胆固醇酯水解酶抗体
抗体英文名：
Lysosomal acid lipase
保质期：
1年
克隆性：
单克隆
数量：
167
供应商：
江西江蓝纯生物试剂有限公司
规格：
100ul/200ul
| 规格： |
100ul |
产品价格： |
¥1580.0 |
| 规格： |
200ul |
产品价格： |
¥2480.0 |
产品货号 : jlcR18592英文名称 : Lysosomal acid lipase中文名称 : 胆固醇酯水解酶抗体别 名 : Acid Cholesteryl Ester Hydrolase; CESD; cholesterol ester hydrolase; cholesterol ester storage disease; Cholesteryl Esterase; Hydrolase deficiency; LAL; LAL deficiency cholesterol ester; LICH_HUMAN; LIPA; LIPA deficiency; Lipase A; lipase A, lysosomal acid, cholesterol esterase; lysosomal acid lipase; lysosomal acid lipase deficiency; Lysosomal acid lipase/cholesteryl ester hydrolase; Sterol esterase. 研究领域 : 肿瘤 细胞生物 信号转导 抗体来源 : Rabbit克隆类型 : Polyclonal交叉反应 : Human, Mouse, Rat, Cow, Horse, Sheep, 产品应用 : ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.分 子 量 : 43kDa细胞定位 : 细胞浆 性 状 : Lyophilized or Liquid浓 度 : 1mg/ml免 疫 原 : KLH conjugated synthetic peptide derived from human Lysosomal acid lipase:101-200/399 亚 型 : IgG纯化方法 : affinity purified by Protein A储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.PubMed : PubMed产品介绍 : This gene encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase). This enzyme functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides. Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2014]Function:Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation.Subcellular Location:Lysosome.DISEASE:Defects in LIPA are the cause of Wolman disease (WOD) [MIM:278000]. WOD is a severe manifestation of LIPA deficiency, leading to the accumulation of cholesteryl esters and triglycerides in most tissues of the body. WOD occurs in infancy and is nearly always fatal before the age of 1 year.Defects in LIPA are the cause of cholesteryl ester storage disease (CESD) [MIM:278000]. CESD is a mild manifestation of LIPA deficiency, leading to the accumulation of cholesteryl esters and triglycerides in most tissues of the body. It is characterized by late-onset.Similarity:Belongs to the AB hydrolase superfamily. Lipase family.SWISS:P38571Gene ID:3988Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
