转录因子DP3/肝癌相关抗原661抗体

货号： jlcR6400 保存条件： -20 ° 浓度： 1mg/ml 应用范围： WB,ELISA等 适应物种： 人/动物/植物 抗体名： 转录因子DP3/肝癌相关抗原661抗体 抗体英文名： TFDP3 保质期： 1年 克隆性： 单克隆 数量： 57 供应商： 江西江蓝纯生物试剂有限公司 规格： 100ul/200ul

规格：	100ul	产品价格：	¥1580.0
规格：	200ul	产品价格：	¥2480.0

产品货号 :  jlcR6400
英文名称 :  TFDP3
中文名称 :  转录因子DP3/肝癌相关抗原661抗体
别   名 :  Cancer/testis antigen 30; CT30; E2F-like; HCA661; Hepatocellular carcinoma-associated antigen 661; TFDP3; Transcription factor Dp family member 3; TFDP3_HUMAN.  
研究领域 :  细胞生物  细胞周期蛋白  转录调节因子  表观遗传学  
抗体来源 :  Rabbit
克隆类型 :  Polyclonal
交叉反应 :   Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit,
产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 :  45kDa
细胞定位 :  细胞核 细胞浆
性    状 :  Lyophilized or Liquid
浓    度 :  1mg/ml
免 疫 原 :  KLH conjugated synthetic peptide derived from human TFDP3:301-405/405
亚    型 :  IgG
纯化方法 :  affinity purified by Protein A
储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed :  PubMed
产品介绍 :   This gene encodes a member of the DP family of transcription factors. These factors heterodimerize with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes. This protein functions as a negative regulator and inhibits the DNA binding and transcriptional activities of E2F factors.

Function:
Competitive inhibitor of E2F-mediated transactivation activity. Impairs E2F-mediated cell-cycle progression from G(1) to S phase.

Subunit:
Heterodimer: with E2F family members. TFDP3/E2F heterodimers do not bind DNA and repress E2F-dependent transcriptional activity.

Subcellular Location:
Nucleus. Cytoplasm. Note=Translocates to the nucleus on heterodimerization with E2F family members.

Tissue Specificity:
Predominantly expressed in testis. Low level of expression in pancreas. Highly expressed in ovarian and colon cancer cell lines.

Similarity:
Belongs to the E2F/DP family.

SWISS:
Q5H9I0

Gene ID:
51270

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品图片