三磷酸肌醇3激酶A抗体

货号： jlcR17184 保存条件： -20 ° 浓度： 1mg/ml 应用范围： WB,ELISA等 适应物种： 人/动物/植物 抗体名： 三磷酸肌醇3激酶A抗体 抗体英文名： ITPKA 保质期： 1年 克隆性： 单克隆 数量： 53 供应商： 江西江蓝纯生物试剂有限公司 规格： 100ul/200ul

规格：	100ul	产品价格：	¥1580.0
规格：	200ul	产品价格：	¥2480.0

产品货号 :  jlcR17184
英文名称 :  ITPKA
中文名称 :  三磷酸肌醇3激酶A抗体
别    名 :  1D myo inositol trisphosphate 3 kinase A; EC 2.7.1.127; Inositol 1 4 5 trisphosphate 3 kinase A; Inositol trisphosphate 3 kinase A; IP3 3 kinase A; IP3K A; IP3KA. IP3KA_HUMAN   
研究领域 :  细胞生物  信号转导  激酶和磷酸酶  
抗体来源 :  Rabbit
克隆类型 :  Polyclonal
交叉反应 :   Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 :  51kDa
细胞定位 :  细胞浆
性    状 :  Lyophilized or Liquid
浓    度 :  1mg/ml
免 疫 原 :  KLH conjugated synthetic peptide derived from human ITPKA:301-400/461
亚    型 :  IgG
纯化方法 :  affinity purified by Protein A
储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed :  PubMed
产品介绍 :   Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.[provided by RefSeq, Apr 2011]

Function:
ITPKA regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of ITPKA is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro. ITPKA and ITPKB are 68% identical in the C-terminus region.

Subcellular Location:
cytosol

Similarity:
Belongs to the inositol phosphokinase (IPK) family.

SWISS:
P23677

Gene ID:
3706

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品图片