CD150(PE conjugated)| CD150 antibody(PE conjugated)

Product Name CD150 antibody(PE conjugated)

Catalog No PAab09790

Packing 100ul

Form liquid

Alternative Name CDw150, Slamf1, Slam, ESTM51, IPO-3, 4933415F16, AA177906

Purification Protein G purified

Purity 95% as determined by SDS-PAGE

Host Rat

Isotype IgG1

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM(signalinglymphocyte activation molecule) orIPO-3. CD150, asingle chain type I transmembranemolecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells.The expression is upregulated upon activation. CD150 expression has been shown to bemaintained onTh1 but notTh2 clones.Tregulatory cells express a relatively high level of CD150.Antibodies against CD150 have been shown to augment IFN-g production byTh1 cells, especiallywhen co-stimulated through the TCR. CD150 associates with the src homology2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to beinvolved in signal transduction. In combination with CD48, CD150 is a useful marker forhematopoieticstem cell studies.

Immunogen signaling lymphocytic activation molecule family member 1

Specificity Mouse

Tested Application FC

Recommended dilution 1：10-1：50

IHC use

WB use

Protein Information

Gene ID

Uniprot ID Q9QUM4

Calculated MW 11kd

Research Area