MYD88 antibody
Product Name MYD88 antibody
Catalog No PAab09835
Packing 100ul
Form liquid
Alternative Name MYD88, MYD88D
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
Immunogen myeloid differentiation primary response gene
Specificity Human, Mouse, Rat
Tested Application ELISA, WB
Recommended dilution WB: 1:500 - 1:2000
IHC use
WB use
Jurkat cells were subjected to SDS PAGE followed by western blot with PAab09835(MYD88 antibody) at dilution of 1:1000
Protein Information
Gene ID 4615
Uniprot ID Q99836
Calculated MW 90 kDa
Research Area Immunology, Signal Transduction