Visfatin| Visfatin antibody

Product Name Visfatin antibody

Catalog No PAab09847

Packing 100ul

Form liquid

Alternative Name 1110035O14Rik, DKFZp666B131, NAmPRTase, NAMPT, PBEF, PBEF1, Pre B cell enhancing factor, VF, VISFATIN

Purification protein A+G purified

Purity 95% as determined by SDS-PAGE

Host Mouse

Isotype IgG2b

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Nicotinamide phosphoribosyltransferase(NAMPT) has two usual synonyms termed Visfatin and PBEF. Its primary role is to catalyze the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD, which is the rate limiting component in the mammalian NAD biosynthesis pathway. NAMPT is localized in cytoplasm and expressed in large amounts in bone marrow, liver tissue, and muscle tissues. NAMPT inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis. NAMPT levels are altered in plasma of patients with type 2 diabetes mellitus(T2DM), and it is now evidenced that NAMPT may plays a role in lipid metabolism.

Immunogen nicotinamide phosphoribosyltransferase

Specificity Human, Mouse, Rat

Tested Application ELISA, WB, IHC, IF

Recommended dilution WB: 1:1000-1:4000; IHC: 1:50-1:500; IF: 1:50-1:500

IHC use Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using PAab09847( Visfatin antibody ) at dilution of 1:200

WB use

rat heart tissue were subjected to SDS PAGE followed by western blot with PAab09847( Visfatin antibody ) at dilution of 1:2000

Protein Information

Gene ID 10135

Uniprot ID P43490

Calculated MW

Research Area Neuroscience, Immunology, Signal Transduction, Metabolism, Cardiovascular