TUBB3 specific| TUBB3 specific antibody

Product Name TUBB3 specific antibody

Catalog No PAab09890

Packing 100ul

Form liquid

Alternative Name TUBB3, TUBB3-specific, Tubj1, Tubulin beta 3 chain, Tubulin beta III, tubulin, beta 3

Purification protein A+G purified

Purity 95% as determined by SDS-PAGE

Host Mouse

Isotype IgG1

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

TUBB3, the class III β tubulin or Tuj1, is selectively expressed in testis and neurons of the central and peripheral nervous system. It has been widely used as a marker for neurons. Aberrant expression of TUBB3 has also been found in various tumors of non-neural origin and can be used as a biomarker for cancer aggressiveness and a marker for the tendency to respond poorly to chemotherapy. This antibody is specific to TUBB3 but not cross-react with other tubulin isoforms.

Immunogen AS160

Specificity Human, Mouse, Rat

Tested Application ELISA, WB, IHC

Recommended dilution WB: 1:5000-1:50000; IHC: 1:50-1:500

IHC use Immunohistochemistry of paraffin-embedded mouse brain tissue slide using PAab09890 (TUBB3 specific antibody) at dilution of 1:200

WB use

SH-SY5Y cells were subjected to SDS PAGE followed by western blot with PAab09890(TUBB3 specific antibody) at dilution of 1:30000

Protein Information

Gene ID 10381

Uniprot ID Q13509

Calculated MW 18 kDa

Research Area Signal Transduction