产品名称:p21蛋白抗体,Anti-P21抗体您的
中文名称:p21蛋白抗体
英文名称:Anti-P21
产品编号:byk-10129R
产品规格:0.1ml/0.2ml
产品用途:科研实验
性 状: Lyophilized or Liquid
浓 度: 1mg/1ml
亚 型: IgG
贮 存: 贮存于-20℃.
相关标记: HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647
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紧密连接蛋白5抗体 Anti-Claudin 5/CLDN5
神经肽S抗体 Anti-NPS/Neuropeptide S
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神经细胞表面蛋白F3抗体 Anti-Contactin-1
Ⅹ型胶原抗体 Anti-Collagen X
Ⅴ型胶原抗体 Anti-Collagen V
抗Ⅵ型胶原抗体 Anti-Collagen VI alpha 1
IV型胶原蛋白/4型胶原蛋白/胶原蛋白4抗体 Anti-Collagen IV
Ⅲ型胶原蛋白/胶原蛋白3/3型胶原蛋白抗体 Anti-Collagen III
Ⅱ型胶原α1蛋白/软骨钙素抗体 Anti-Collagen II/Chondrocalcin
Ⅰ型胶原抗体 Anti-Collagen I
凝集胎盘蛋白1抗体 Anti-COLEC12
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抗体规律
(1)初次反应产生抗体:当抗原一次进入机体时,需经一定的潜伏期才能产生抗体,且抗体产生的量也不多,在体内维持的时间也较短。
(2)再次反应产生抗体:当相同抗原第二次进入机体后,开始时,由于原有抗体中的一部分与再次进入的抗原结合,可使原有抗体量略为降低。随后,抗体效价迅速大量增加,可比初次反应产生的多几倍到几十倍,在体内留存的时间亦较长。
(3)回忆反应产生抗体:由抗原刺激机体产生的抗体,经过一定时间后可逐渐消失。此时若再次接触抗原,可使已消失的抗体快速上升。如再次刺激机体的抗原与初次相同,则称为特异性回忆反应;若与初次反应不同,则称为非特异性回忆反应。非特异性回忆反应引起的抗体的上升是暂时性的,短时间内即很快下降。
p21蛋白抗体,Anti-P21抗体您的 产品详情:
This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation. Two alternatively spliced variants, which encode an identical protein, have been reported. Two families of cyclin dependent kinase inhibitors (CKIs) have been identified. The p21WAF1/Cip1 family inhibits all kinases involved in the G1/S transition. The p16INK4a family inhibits Cdk4 and Cdk6 specifically.