USP9X| USP9X antibody

货号  PAab09344

蛋白别名  Deubiquitinating enzyme FAF X antibody, DFFRX antibody, FAF antibody, FAM antibody, Fat facets in mammals antibody, hFAM antibody, Ubiquitin thiolesterase FAF X antibody, USP9 antibody, USP9X

蛋白介绍

Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Regulates chromosome alignment and segregation in mitosis by regulating the localization of BIRC5/survivin to mitotic centromeres. Specifically hydrolyzes both 'Lys-29'- and 'Lys-33'-linked polyubiquitins chains. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Involved in axonal growth and neuronal cell migration.

产品描述

建议稀释比例

WB :1:500-1:5000;IF:1:10-1:100;IHC:1：20-1：200;IP:1：200-1：2000

IHC

Immunohistochemistry of paraffin-embedded human pancreas cancer tissue slide using PAab09344( USP9X Antibody) at dilution of 1:50

Western blot

HEK-293 cells were subjected to SDS PAGE followed by western blot with PAab09344(USP9X antibody) at dilution of 1:500(本抗体仅供体外科研用途，不可用于临床诊断!)

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