货号：
PAab05541
抗体名：
anti-NANOG 抗体,NANOG 抗体
抗体英文名：
anti-NANOG antibody,NANOG antibody
浓度：
≥95% as determined by SDS-PAGE
应用范围：
ELISA,IF,WB
宿主：
Rabbit
供应商：
LSM bio
数量：
50
保质期：
12 month
适应物种：
Human, Mouse
克隆性：
单克隆
保存条件：
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
形态：
liquid
亚型：
IgG
免疫原：
Nanog homeobox
规格：
100μg
NANOG抗体| NANOG antibody 货号 PAab05541
蛋白别名
蛋白介绍
Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'- [CG][GA][CG]C[GC]ATTAN[GC]-3'. Able to autorepress its expression in differentiating (ES) cells: binds to its own promoter following interaction with ZNF281/ZFP281, leading to recruitment of the NuRD complex and subsequent repression of expression. When overexpressed, promotes cells to enter into S phase and proliferation.
产品描述
anti-NANOG antibody is a Rabbit Polyclonal antibody againstNANOG.. 建议稀释比例
IHC
Western blot
(本抗体仅供体外科研用途，不可用于临床诊断!)
武汉维克赛思科技有限公司
地址：武汉东湖新技术开发区东信路光谷创业街10栋
联系人：童经理
联系电话：13118103892
Email: info@vecscience.com
微信：13118103892
QQ: 3128136151
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