谷胱甘肽硫转移酶pi基因/Glutathione S Transferase pi抗体_详细资料

产品信息

货号： jlcR23151 保存条件： -20 ° 浓度： 1mg/ml 应用范围： WB,ELISA等适应物种：人/动物/植物抗体名：谷胱甘肽硫转移酶pi基因/Glutathione S Transferase pi抗体抗体英文名： GSTP1 保质期： 1年克隆性：单克隆数量： 84 供应商：江西江蓝纯生物试剂有限公司规格： 100ul/200ul

规格： 100ul 产品价格： ¥1580.0

规格： 200ul 产品价格： ¥2480.0

产品货号 :  jlcR23151
英文名称 : GSTP1
中文名称 : 谷胱甘肽硫转移酶pi基因/Glutathione S Transferase pi抗体
别    名 : Glutathione S-Transferase pi; GST-Pi; DFN7; Gst-P1; FAEES3; Fatty Acid Ethyl Ester Synthase III; Glutathione S Transferase Pi; GST3; GSTP1; GST pi; PI; GSTP1_MOUSE.
研究领域 : 肿瘤细胞生物免疫学神经生物学转录调节因子
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 :   Mouse, Rat,
产品应用 : WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分子量 : 23kDa
细胞定位 : 细胞浆
性    状 : Lyophilized or Liquid
浓    度 : 1mg/ml
免疫原 : KLH conjugated synthetic peptide derived from mouse GSTP1:81-180/210
亚    型 : IgG
纯化方法 : affinity purified by Protein A
储存液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍 :  Glutathione S-transferases (GSTs) function in the metabolic detoxification of various environmental carcinogens and lipid hydroperoxides. Members of the murine GSTP (glutathione S-transferase pi) family, termed Gstp1 and Gstp2, are linked to drug resistance and are markers for many cancers. Gstp proteins modulate cell signaling by interacting with c-Jun N-terminal kinase (JNK), and may play a protective role in the development of spontaneous tumors. Gstp has been found in substantia nigra and may be associated with reactive oxygen species-induced neurological disorders such as Parkinson’s disease and may additionally protect against endothelial dysfunction induced by tobacco smoke exposure.

Function:
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.

Subunit:
Homodimer.

Tissue Specificity:
Ubiquitously expressed.

Similarity:
Belongs to the GST superfamily. Pi family.
Contains 1 GST C-terminal domain.
Contains 1 GST N-terminal domain.

SWISS:
P09211

Gene ID:
14870

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

GST-Pi是GST家族中的一种主要的同工酶，广泛存在于全身器官中，尤以肝肾含量高，具有功能。在多种肿瘤中高表达。目前认为是肿瘤细胞产生耐药的一种标记，与肿瘤的耐药（阿霉素、顺铂、氮、环磷酰胺和瘤可宁等）有关。该抗体主要用于细胞耐YF面的研究。

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规格：	100ul	产品价格：	¥1580.0
规格：	200ul	产品价格：	¥2480.0

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