Product Information:
Product name | VAV3 Polyclonal Antibody |
Isotype | IgG |
Form | Lyophilized or Liquid |
Tested applications | WB,ELISA,IHC |
Species reactivity | Human,Mouse |
Host Species | Rabbit |
Purity | Affinity purification |
Immunogen Information:
Immunogen | Recombinant protein of human VAV3 |
Calculated molecular weight | 32kDa/86kDa/97kDa/100kDa |
Observed molecular weight | 105kDa |
Swiss Prot | Q9UKW4 |
Gene ID (NCBI) | 10451 |
Alternative Names | vav guanine nucleotide exchange factor 3 |
Application Notes:
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB | 1:200 - 1:2000 |
IHC | 1:50 - 1:500 |
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Western blot analysis of extracts of various cell lines, using VAV3 antibody. | | |
Background:
This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Storage:
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |