品名 | anti- Phospho-CHEK1-S280 antibody |
货号 | FNab09816 |
规格 | 100µg |
状态 | liquid |
纯化方法 | Immunogen affinity purified |
纯度 | ≥95% as determined by SDS-PAGE |
宿主 | Rabbit |
亚型 | IgG |
存储 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 24 months(Avoid repeated freeze / thaw cycles.) |
背景介绍 | The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC2 protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. |
免疫原 | Phospho-CHEK1-S280 |
别称 | CHK1 |
分子量 | 60 kDa |
Uniprot ID | O14757 |
适用种属 | Human, Mouse |
验证应用 | ELISA, WB, IHC, IF |
建议稀释比例 | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200 |
图片 | | Immunofluorescence analysis of MCF-7 cells using FNab09816. Blue: DAPI for nuclear staining. |
| HT-29 cells were subjected to SDS PAGE followed by western blot with FNab09816 at dilution of 1:1000 |
注意事项 | Phospho-CHEK1-S280 antibody|Phospho-CHEK1-S280抗体仅供科研使用 |
产品链接 | https://www.fn-test.cn/product/FNab09816/ |