品名 | anti- Alpha B Crystallin antibody |
货号 | FNab00325 |
规格 | 100µg |
状态 | liquid |
纯化方法 | Immunogen affinity purified |
纯度 | ≥95% as determined by SDS-PAGE |
宿主 | Rabbit |
亚型 | IgG |
存储 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 24 months(Avoid repeated freeze / thaw cycles.) |
背景介绍 | Alpha B-crystallin, encoded by CRYAB gene, is multifunctional, serving as both a major structural protein in the lens and a small heat-shock protein in other tissues in mammals. Alpha B-crystallin may contribute to the transparency and refractive index of the lens. Single nucleotide polymorphisms(SNPs) in the promoter region of CRYAB gene have been associated with in multiple sclerosis. Mutations in the CRYAB gene cause distinct clinical phenotypes including isolated posterior polar cataract, myofibrillar myopathy, cardiomyopathy, or a multisystemic disorder combining all these features. Impairment of alpha-B crystallin dimerization may be relevant to the pathogenesis of these disorders. |
免疫原 | crystallin, alpha B |
别称 | Alpha B Crystallin, Alpha crystallin B chain, Alpha(B) crystallin, CRYA2, CRYAB, crystallin, alpha B, CTPP2, Heat shock protein beta 5, HSPB5, Rosenthal fiber component |
分子量 | 20 kDa |
Uniprot ID | P02511 |
适用种属 | Human, Mouse, Rat |
验证应用 | ELISA, WB, IHC, IP |
建议稀释比例 | WB: 1:500-1:5000; IHC: 1:20-1:200; IP: 1:200-1:2000 |
图片 |  | Immunohistochemistry of paraffin-embedded mouse heart tissue using FNab00325(CRYAB antibody) at dilution of 1:100 |
 | human heart tissue were subjected to SDS PAGE followed by western blot with FNab00325(CRYAB antibody) at dilution of 1:500 |
注意事项 | Alpha B Crystallin antibody|Alpha B Crystallin抗体仅供科研使用 |
产品链接 | https://www.fn-test.cn/product/FNab00325/ |