品名 | anti- AKR1C3 antibody |
货号 | FNab00262 |
规格 | 100µg |
状态 | liquid |
纯化方法 | Immunogen affinity purified |
纯度 | ≥95% as determined by SDS-PAGE |
宿主 | Rabbit |
亚型 | IgG |
存储 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 24 months(Avoid repeated freeze / thaw cycles.) |
背景介绍 | This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha, 11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene. |
免疫原 | aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) |
别称 | 17 beta HSD 5, 3 alpha HSD type 2, 3 alpha HSD type II, brain, AKR1C3, DD 3, DD3, DDX, Dihydrodiol dehydrogenase 3, HA1753, HAKRB, HAKRe, hluPGFS, HSD17B5, Indanol dehydrogenase, KIAA0119, PGFS, Prostaglandin F synthase |
分子量 | 37 kDa |
Uniprot ID | P42330 |
适用种属 | Human, Rat |
验证应用 | ELISA, WB, IHC, IF |
建议稀释比例 | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200 |
图片 |  | Immunohistochemistry of paraffin-embedded rat heart using FNab00262(AKR1C3 antibody) at dilution of 1:100 |
 | HepG2 cells were subjected to SDS PAGE followed by western blot with FNab00262(AKR1C3 antibody) at dilution of 1:1000 |
注意事项 | AKR1C3 antibody|AKR1C3抗体仅供科研使用 |
产品链接 | https://www.fn-test.cn/product/FNab00262/ |