品名 | anti- Caspase 10 antibody |
货号 | FNab01285 |
规格 | 100µg |
状态 | liquid |
纯化方法 | Immunogen affinity purified |
纯度 | ≥95% as determined by SDS-PAGE |
宿主 | Rabbit |
亚型 | IgG |
存储 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 24 months(Avoid repeated freeze / thaw cycles.) |
背景介绍 | This gene encodes a protein which is a member of the cysteine-aspartic acid protease(caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
免疫原 | caspase 10, apoptosis-related cysteine peptidase |
别称 | ALPS2, Apoptotic protease Mch 4, CASP 10, CASP10, Caspase 10, Caspase 10/p23/17/p12, Caspase10, FLICE2, ICE like apoptotic protease 4, MCH4 |
分子量 | 59kd |
Uniprot ID | Q92851 |
适用种属 | Human |
验证应用 | ELISA, WB, IHC, IF, IP |
建议稀释比例 | WB: 1:500-1:1000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200 |
图片 | | Immunohistochemistry of paraffin-embedded human endometrial cancer using FNab01285(CASP10 antibody) at dilution of 1:100 |
| HeLa cells were subjected to SDS PAGE followed by western blot with FNab01285(CASP10 antibody) at dilution of 1:300 |
注意事项 | Caspase 10 antibody|Caspase 10抗体仅供科研使用 |
产品链接 | https://www.fn-test.cn/product/FNab01285/ |