品名 | anti- CRK antibody |
货号 | FNab01981 |
规格 | 100µg |
状态 | liquid |
纯化方法 | Immunogen affinity purified |
纯度 | ≥95% as determined by SDS-PAGE |
宿主 | Rabbit |
亚型 | IgG |
存储 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 24 months(Avoid repeated freeze / thaw cycles.) |
背景介绍 | This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. |
免疫原 | v-crk sarcoma virus CT10 oncogene homolog (avian) |
别称 |
分子量 | 37 kDa |
Uniprot ID | P46108 |
适用种属 | Human, Mouse |
验证应用 | ELISA, WB, IHC |
建议稀释比例 | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
图片 | | Immunohistochemistry of paraffin-embedded human liver cancer using FNab01981(CRK antibody) at dilution of 1:100 |
| MCF7 cells were subjected to SDS PAGE followed by western blot with FNab01981(CRK antibody) at dilution of 1:1000 |
注意事项 | CRK antibody|CRK抗体仅供科研使用 |
产品链接 | https://www.fn-test.cn/product/FNab01981/ |