品名 | anti- Collagen Type IV antibody |
货号 | FNab01844 |
规格 | 100µg |
状态 | liquid |
纯化方法 | Immunogen affinity purified |
纯度 | ≥95% as determined by SDS-PAGE |
宿主 | Rabbit |
亚型 | IgG |
存储 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 24 months(Avoid repeated freeze / thaw cycles.) |
背景介绍 | Type IV collagen is the major structural component of glomerular basement membranes(GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.Canstatin, a cleavage product corresponding to the collagen alpha 2(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity. It inhibits proliferation and migration of endothelial cells, reduces mitochondrial membrane potential, and induces apoptosis. Specifically induces Fas-dependent apoptosis and activates procaspase-8 and-9 activity. Ligand for alphavbeta3 and alphavbeta5 integrins. |
免疫原 | collagen, type IV, alpha 2 |
别称 | COL4A2, Collagen alpha 2(IV) chain, Collagen Type IV, collagen, type IV, alpha 2, DKFZp686I14213, FLJ22259 |
分子量 | 200 kDa |
Uniprot ID | P08572 |
适用种属 | Human, Mouse, Rat |
验证应用 | ELISA, IHC |
建议稀释比例 | IHC: 1:20-1:200 |
图片 | |
| Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab01844(Collagen Type IV antibody) at dilution of 1:50 |
注意事项 | Collagen Type IV antibody|Collagen Type IV抗体仅供科研使用 |
产品链接 | https://www.fn-test.cn/product/FNab01844/ |