品名 | anti- EBI3 antibody |
货号 | FNab02615 |
规格 | 100µg |
状态 | liquid |
纯化方法 | Immunogen affinity purified |
纯度 | ≥95% as determined by SDS-PAGE |
宿主 | Rabbit |
亚型 | IgG |
存储 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 24 months(Avoid repeated freeze / thaw cycles.) |
背景介绍 | Associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro-and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells(TH1), type 2 effector cells(TH2) and IL17 producing helper T-cells(TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines. |
免疫原 | Epstein-Barr virus induced 3 |
别称 | IL27B |
分子量 | 25-35 kDa |
Uniprot ID | Q14213 |
适用种属 | Human |
验证应用 | ELISA, WB |
建议稀释比例 |
图片 | |
| MCF7 cells were subjected to SDS PAGE followed by western blot with FNab02615(EBI3 antibody) at dilution of 1:300 |
注意事项 | EBI3 antibody|EBI3抗体仅供科研使用 |
产品链接 | https://www.fn-test.cn/product/FNab02615/ |