品名 | anti- HLA class I(HLA-A) antibody |
货号 | FNab03895 |
规格 | 100µg |
状态 | liquid |
纯化方法 | Immunogen affinity purified |
纯度 | ≥95% as determined by SDS-PAGE |
宿主 | Rabbit |
亚型 | IgG |
存储 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 24 months(Avoid repeated freeze / thaw cycles.) |
背景介绍 | HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described. |
免疫原 | major histocompatibility complex, class I, A |
别称 | HLA A, HLAA, HLA-A |
分子量 | 44 kDa |
Uniprot ID | P04439/P30443 |
适用种属 | Human, Mouse |
验证应用 | ELISA, WB, IHC |
建议稀释比例 | WB: 1:500-1:2000; IHC: 1:50-1:200 |
图片 |  | Immunohistochemistry of paraffin-embedded human esophagus using FNab03895(HLA class I(HLA-A) antibody) at dilution of 1:100 |
 | HepG2 cells were subjected to SDS PAGE followed by western blot with FNab03895(HLA class I(HLA-A) antibody) at dilution of 1:1000 |
注意事项 | HLA class I(HLA-A) antibody|HLA class I(HLA-A)抗体仅供科研使用 |
产品链接 | https://www.fn-test.cn/product/FNab03895/ |