品名 | anti- HER2/ErbB2 antibody |
货号 | FNab03834 |
规格 | 100µg |
状态 | liquid |
纯化方法 | Immunogen affinity purified |
纯度 | ≥95% as determined by SDS-PAGE |
宿主 | Rabbit |
亚型 | IgG |
存储 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 24 months(Avoid repeated freeze / thaw cycles.) |
背景介绍 | This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. |
免疫原 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog(avian) |
别称 | CD340, ERBB2, HER 2, HER 2/neu, HER2, MLN 19, MLN19, NEU, NGL, p185, p185erbB2, Proto oncogene c ErbB 2, Proto oncogene Neu, TKR1 |
分子量 | 185 kDa |
Uniprot ID | P04626 |
适用种属 | Human |
验证应用 | ELISA, WB, IHC, IF |
建议稀释比例 | WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200 |
图片 | | Immunohistochemistry of paraffin-embedded human breast cancer using FNab03834(ERBB2 antibody) at dilution of 1:50 |
| HeLa cells were subjected to SDS PAGE followed by western blot with FNab03834(ERBB2 antibody) at dilution of 1:500 |
注意事项 | HER2/ErbB2 antibody|HER2/ErbB2抗体仅供科研使用 |
产品链接 | https://www.fn-test.cn/product/FNab03834/ |