NOTCH1 antibody|NOTCH1抗体

货号： FNab05799 抗体名： anti- NOTCH1 antibody 抗体英文名： anti- NOTCH1 antibody 靶点： 武汉菲恩生物科技有限公司 浓度： ≥95% as determined by SDS-PAGE 应用范围： ELISA, WB, IHC, IP 宿主： Rabbit 供应商： 科研级别 数量： 2年 -20℃ 适应物种： 98 标记物： polyclonal 克隆性： 单克隆 保存条件： PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 24 months(Avoid repeated freeze / thaw cycles.) 形态： liquid 亚型： IgG 免疫原： Notch homolog 1, translocation-associated(Drosophila) 规格： 100µg

NOTCH1 antibody|NOTCH1抗体具有高亲合力和高特异性深受国外市场认可；菲恩生物专注于免疫学、细胞生物学、肿瘤、神经生物学等领域。
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产品介绍

品名	anti- NOTCH1 antibody
货号	FNab05799
规格	100µg
状态	liquid
纯化方法	Immunogen affinity purified
纯度	≥95% as determined by SDS-PAGE
宿主	Rabbit
亚型	IgG
存储	PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 24 months(Avoid repeated freeze / thaw cycles.)
背景介绍	Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain(NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the maturation of both CD4+ and CD8+ cells in the thymus. Important for follicular differentiation and possibly cell fate selection within the follicle. During cerebellar development, functions as a receptor for neuronal DNER and is involved in the differentiation of Bergmann glia. Represses neuronal and myogenic differentiation. May play an essential role in postimplantation development, probably in some aspect of cell specification and/or differentiation. May be involved in mesoderm development, somite formation and neurogenesis. May enhance HIF1A function by sequestering HIF1AN away from HIF1A. Required for the THBS4 function in regulating protective astrogenesis from the subventricular zone(SVZ) niche after injury. Involved in determination of left/right symmetry by modulating the balance between motile and immotile(sensory) cilia at the left-right organiser(LRO).The antibody is specific to NOTCH1. It can recognize the full length NOTCH1(270 kDa) and all the three cleaved NOTCH1 forms 110-120 kDa.
免疫原	Notch homolog 1, translocation-associated(Drosophila)
别称	lin 12, Mis6, Notch1, Tan1
分子量	270 kDa,120kd
Uniprot ID	P46531
适用种属	Human, Mouse, Rat
验证应用	ELISA, WB, IHC, IP
建议稀释比例	WB: 1:500-1:1000; IP: 1:200-1:1000; IHC: 1:50-1:500
图片		Immunohistochemistry of paraffin-embedded mouse brain tissue tissue slide using FNab05799(NOTCH1 Antibody) at dilution of 1:200
		human brain tissue were subjected to SDS PAGE followed by western blot with FNab05799(NOTCH1 antibody) at dilution of 1:500
注意事项	NOTCH1 antibody|NOTCH1抗体仅供科研使用
产品链接	https://www.fn-test.cn/product/FNab05799/

菲恩简介
  菲恩生物面向国际市场专业研发，生产和销售ELISA试剂盒、抗体、重组蛋白及相关试剂,主要应用于免疫学、细胞生物学、肿瘤、神经生物学等相关领域的生命科学研究。

菲恩生物位置
  菲恩生物坐落于高新区、生物产业基地--武汉光谷生物城（biolake）。

菲恩优势
  1、专业科研试剂生产商，具有独立的现代化研发ZX和GMP标准的生产车间，产品高质控，高纯度，高活性，成本更低，价格竞争力强。
  2、专业科研试剂的研发，专注于免疫学、细胞生物学、肿瘤、神经生物学等领域，每年新增研发产品千余种。产品数量、批间批内差、亲合力、特异性达国际标准，
菲恩生物—科研好帮手，专业生产商。

研究领域
  免疫学、细胞生物学、肿瘤、神经生物学等相关领域的生命科学研究

质量保证
  菲恩生物建有现代化的研发ZX和符合GMP标准的生产车间，整体通过ISO 9001:2015质量管理体系认证。

产品数量
  ELISA试剂盒：18个种属：人、大鼠、小鼠、猪、牛、其他稀有种属
  主要指标：
    1、细胞因子：IL、Selectin、CSF、TNF、IF、TGF、chemokine、CAM、IGF、CR等；
    2、心肌梗塞：cTn，MYO，CRP等；
    3、内分泌：TH、Pg、Testosterone、GH、Cytokine receptor、Endothelin、COR、BGP、PRL、ACTH、FSH、Estradiol等；
    4、肝纤维化：HA、MMP、LN等；
    5、肿瘤标志物：TNF、TNFSF10、TNFRSF1A等；
    6、特种蛋白：Ig、CRP、ALB、FE、TRF等。
  抗体：兔多抗、鼠单抗种类丰富，一抗1万余种，二抗100多种；
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