品名 | anti- Myelin basic protein antibody |
货号 | FNab05465 |
规格 | 100µg |
状态 | liquid |
纯化方法 | Immunogen affinity purified |
纯度 | ≥95% as determined by SDS-PAGE |
宿主 | Rabbit |
亚型 | IgG |
存储 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 24 months(Avoid repeated freeze / thaw cycles.) |
背景介绍 | The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes. |
免疫原 | myelin basic protein |
别称 | MBP, Myelin A1 protein, Myelin basic protein |
分子量 | 34 kDa |
Uniprot ID | P02686 |
适用种属 | Human, Mouse, Rat |
验证应用 | ELISA, WB, IHC, IF |
建议稀释比例 | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200 |
图片 | ![](http://item.yiqi.com/pic/ConPic/4/FNab05465.jpg) | Immunohistochemistry of paraffin-embedded rat kidney tissue slide using FNab05465( MBP Antibody) at dilution of 1:200 |
![](http://item.yiqi.com/pic/ConPic/4/FNab05465.jpg) | mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab05465( MBP Antibody) at dilution of 1:1000 |
注意事项 | Myelin basic protein antibody|Myelin basic protein抗体仅供科研使用 |
产品链接 | https://www.fn-test.cn/product/FNab05465/ |