品名 | anti- TRPV6 antibody |
货号 | FNab09030 |
规格 | 100µg |
状态 | liquid |
纯化方法 | Immunogen affinity purified |
纯度 | ≥95% as determined by SDS-PAGE |
宿主 | Rabbit |
亚型 | IgG |
存储 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 24 months(Avoid repeated freeze / thaw cycles.) |
背景介绍 | Calcium selective cation channel that mediates Ca(2+) uptake in various tissues, including the intestine(PubMed:11097838, PubMed:11278579, PubMed:11248124 PubMed:15184369, PubMed:23612980). Important for normal Ca(2+) ion homeostasis in the body, including bone and skin(By similarity). The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification(PubMed:15184369). Inactivation includes both a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin-dependent mechanism; the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating. |
免疫原 | transient receptor potential cation channel, subfamily V, member 6 |
别称 | ABP/ZF, Calcium transport protein 1, CaT L, CaT like, CAT1, CATL, ECAC2, Epithelial calcium channel 2, HSA277909, LP6728, TRPV6, ZFAB |
分子量 | 82 kDa, Observed 70 kDa |
Uniprot ID | Q9H1D0 |
适用种属 | Human, Mouse, Rat |
验证应用 | ELISA, IF, WB, IP |
建议稀释比例 | WB: 1:500-1:5000; IP: 1:200-1:1000; IF: 1:10-1:100 |
图片 |  |
 | human placenta tissue were subjected to SDS PAGE followed by western blot with FNab09030(TRPV6 Antibody) at dilution of 1:1000 |
注意事项 | TRPV6 antibody|TRPV6抗体仅供科研使用 |
产品链接 | https://www.fn-test.cn/product/FNab09030/ |