品名 | anti- FAS/CD95 antibody |
货号 | FNab03017 |
规格 | 100µg |
状态 | liquid |
纯化方法 | Protein A+G purification |
纯度 | ≥95% as determined by SDS-PAGE |
宿主 | Mouse |
亚型 | IgG2a |
存储 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 24 months(Avoid repeated freeze / thaw cycles.) |
背景介绍 | Fas(CD95/APO-1) is a transmembrane glycoprotein belonging to the tumor necrosis factor(TNF) receptor superfamily. It can mediates apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex(DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The molecular mass of native Fas is 38 kDa, the high molecular weight form(40-55 kDa) of Fas is due to glycosylation. |
免疫原 | Fas(TNF receptor superfamily, member 6) |
别称 | ALPS1A, APO 1, Apo 1 antigen, APT1, CD95, FAS, FAS1, FASLG receptor, FASTM, TNFRSF6 |
分子量 | 38-45 kDa |
Uniprot ID | P25445 |
适用种属 | Human, Mouse |
验证应用 | ELISA, WB, FC,IHC |
建议稀释比例 | WB: 1:1000-1:8000; IHC: 1:50-1:500 |
图片 |  | Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using FNab03017(FAS/CD95 antibody) at dilution of 1:200. |
 | HeLa cells were subjected to SDS PAGE followed by western blot with FNab03017(FAS/CD95 antibody) at dilution of 1:4000 |
注意事项 | FAS/CD95 antibody|FAS/CD95抗体仅供科研使用 |
产品链接 | https://www.fn-test.cn/product/FNab03017/ |