品名 | anti- 4EBP1 antibody |
货号 | FNab00006 |
规格 | 100µg |
状态 | liquid |
纯化方法 | Protein A+G purification |
纯度 | ≥95% as determined by SDS-PAGE |
宿主 | Mouse |
亚型 | IgG2b |
存储 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 24 months(Avoid repeated freeze / thaw cycles.) |
背景介绍 | Eukaryotic translation initiation factor 4E-binding protein 1(4EBP1), is a member of 4EBPs family, which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E, thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors, hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1, alpha, beta and gamma. |
免疫原 | eukaryotic translation initiation factor 4E binding protein 1 |
别称 | 4E BP1, 4EBP1, BP 1, eIF4E binding protein 1, EIF4EBP1, PHAS I |
分子量 | 12 kDa |
Uniprot ID | Q13541 |
适用种属 | Human, Mouse |
验证应用 | ELISA, WB, IHC |
建议稀释比例 | WB: 1:1000-1:10000; IHC: 1:20-1:200; IF: 1:20-1:200 |
图片 | | Immunohistochemistry of paraffin-embedded human pancreas slide using FNab00006(4EBP1 Antibody) at dilution of 1:50 |
| K-562 cells were subjected to SDS PAGE followed by western blot with FNab00006(4EBP1 antibody) at dilution of 1:2000 |
注意事项 | 4EBP1 antibody|4EBP1抗体仅供科研使用 |
产品链接 | https://www.fn-test.cn/product/FNab00006/ |