Tissue Transglutaminase from Human, Recombinant

Website：https://www.creative-enzymes.com/product/tissue-transglutaminase-from-human-recombinant_1857.html；Description：Celiac disease is an enteropathy that is characterized by intestinal lesions of variable severity. Tissue-type transglutaminase (tTG) is believed to be the predominant autoantigen for celiac disease and the corresponding autoantibodies show higher sensitivity and specificity than anti-gliadin antibodies. Highly pure recombinant human tTG is now available to replace the traditionally used tTG fraction from guinea pig. Tissue-type transglutaminase antigens have been specifically modified for improved handling: exchange of an active site amino acid eliminates the protein cross-linking activity of the enzyme, while maintaining the native three-dimensional structure and the enzyme's secondary GTPase activity. This engineering assures reproducible properties of the antigen preparations through the absence of variable and ill-defined covalent aggregates of tTG antigen and host cell proteins.；Source：Sf9 insect cells；Species：Human；Form：；Enzyme Commission Number：EC 2.3.2.13；Activity：；Unit Definition：；Synonyms：Protein-glutamine gamma-glutamyltransferase 2; EC 2.3.2.13; Tissue transglutaminase; TGase C; TGC; TG(C); Transglutaminase-2; TGase-H; TG2; TGM2；Purity：Greater than 95% as determined by SDS-PAGE.；Inhibitors：；了解更多产品请留言，或 直接与孚博生物销售人员联系联系人： 邢先生 电话：13260236521 | 固话：010-56146401 | QQ：20493615 | Email：info@f-biology.com