D-2-Hydroxyglutarate Dehydrogenase from Acidaminococcus fermentans, Recombinant

Website：https://www.creative-enzymes.com/product/d2hydroxyglutarate-dehydrogenase-from-acidaminococcus-fermentans-recombinant_16056.html；Description：D-2-hydroxyglutarate (D2HG) level is significantly increased in metabolic diseases and various cancers such as acute myeloid leukemia. Studies suggest that the detection of D2HG serves as a biomarker assay related to IDH (isocitrate dehydrogenase) mutations. D2HGDH is a special NAD-dependent enzyme which reacts with D2HG specifically and converts D2HG to α-ketoglutarate. D2HGDH is a key enzyme to distinguish between two metabolites, D2HG and L-2-hydroxyglutarate (L2HG), during biomarker assays.；Source：E. coli；Species：Acidaminococcus fermentans；Form：Lyophilized in 50mM Tris, pH 8 without any additives.；Enzyme Commission Number：EC 1.1.99.39；Activity：> 90,000 mU/mg；Unit Definition：One unit is the amount of enzyme that reduces 1.0 µmole of NAD+ to NADH per min. at pH 8 at 37°C.)；Synonyms：D-2-hydroxyglutarate dehydrogenase; D2HGDH; D2HGD；Purity：> 99% by SDS - PAGE；Inhibitors：；了解更多产品请留言，或 直接与孚博生物销售人员联系联系人： 邢先生 电话：13260236521 | 固话：010-56146401 | QQ：20493615 | Email：info@f-biology.com