重组人戈那瑞林,人黄体生成素释放激素

产品英文名称：
Recombinant Human Leutenizing hormone Releasing Hormone (Gonadorelin)

英文简称:
LHRH

中文名称:
重组人戈那瑞林,人黄体生成素释放激素

背景资料:
Gonadotropin-releasing hormone 1 （GNRH1）， also known as Luteinising-hormone releasing hormone （LHRH）， is a peptide hormone responsible for the release of FSH and LH from the anterior pituitary. GNRH1 is synthesized and released by the hypothalamus.At the pituitary， GNRH1 stimulates the synthesis and secretion of the gonadotropins follicle-stimulating hormone （FSH） and luteinizing hormone （LH）. These processes are controlled by the size and frequency of GNRH1 pulses， as well as by fLutenizing Hormone Releasing Hormone Human Recombinant is a heterodimeric， glycosylated， polypeptide chain consisting of two non-covalently linked subunits a and b of 92 and 121 amino acids respectively.The carobhydrate chain attachment to the LHRH protein core accurs via N- but not O-linkage. The N-glycosilation sites are Asn-52 and Asn-78 for the a subunit and Asn-30 for the b subunit. The b chain has an N-glycosilation site and its structure and glycosilation pattern are very similar to that of pituitary LHRH.The LHRH is purified by proprietary chromatographic techniques.dback from androgens and estrogens. Low requency GNRH1 pulses lead to FSH release， whereas high frequency GNRH1 pulses stimulate LH release.There are diSaccharomyces cerevisiae.erences in GNRH1 secretion betwLutenizing Hormone Releasing Hormone Human Recombinant is a heterodimeric， glycosylated， polypeptide chain consisting of two non-covalently linked subunits a and b of 92 and 121 amino acids respectively.The carobhydrate chain attachment to the LHRH protein core accurs via N- but not O-linkage. The N-glycosilation sites are Asn-52 and Asn-78 for the a subunit and Asn-30 for the b subunit. The b chain has an N-glycosilation site and its structure and glycosilation pattern are very similar to that of pituitary LHRH.The LHRH is purified by proprietary chromatographic techniques.n males and females. In males， GNRH1 is secreted in pulses at a constant frequency， but in females the frequency of the pulses varies during the menstrual cycle and there is a large surge of GNRH1 just before ovulation.GNRH1 secretion is pulsatile in all vertebrates， and is necessary for correct reproductive function. Thus， a single hormone， GNRH1， controls a complex process of follicular growth， ovulation， and corpus luteum maintenance in the female， and spermatogenesis in the male.

产品描述:
Lutenizing Hormone Releasing Hormone Human Recombinant is a heterodimeric， glycosylated， polypeptide chain consisting of two non-covalently linked subunits a and b of 92 and 121 amino acids respectively.The carobhydrate chain attachment to the LHRH protein core accurs via N- but not O-linkage. The N-glycosilation sites are Asn-52 and Asn-78 for the a subunit and Asn-30 for the b subunit. The b chain has an N-glycosilation site and its structure and glycosilation pattern are very similar to that of pituitary LHRH.The LHRH is purified by proprietary chromatographic techniques.
来源宿主:
Saccharomyces cerevisiae.

序列:


溶解建议:
提供的重组人戈那瑞林，人黄体生成素释放激素产品为白色无菌冻干粉末.

保存建议：
Lyophilized LHRH although stable at room temperature for 3 weeks， should be stored desiccated below -18℃. Upon reconstitution LNRH should be stored at 4℃ between 2-7 days and for future use below-18℃.For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.Please prevent freeze-thaw cycles.
其他简介：

  ProSpec是一家细胞因子蛋白及相关抗体生产和研发品Pai。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种Z多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。