兰乐肽

产品英文名称：
Lanreotide

英文简称:
Lanreotide

中文名称:
兰乐肽

背景资料:


产品描述:
Lanreotide is a peptide inhibitor of a number of endocrine， neuroendocrine， exocrine and paracrine functions. It shows good ainity for peripheral somatostatin receptors （anterior pituitary and pancreatic）. In contrast， its ainity for central receptors is much lower. This profile confers a good specificity of action at the level of growth hormone and digestive hormone secretion. Lanreotide shows a much longer duration of action than natural somatostatin. In addition， its marked selectivity for the secretion of growth hormone， compared to that of insulin， makes it a suitable candidate for the treatment of acromegaly. By inhibiting the synthesis of thyroid stimulating hormone （TSH）， lanreotide also normalised thyroid function of patients with thyrotrophin secreting adenomas in 50% （8/16） of the per-protocol population treated for 6 months. There was no significant reduction in the size of the adenoma. Furthermore， the inhibitory action of lanreotide on intestinal exocrine secretion， digestive hormones and cellular proliferation mechanisms is suited to the symptomatic treatment of endocrine digestive tumours， especially carcinoids. Lanreotide is an octapeptide， an analogue of a naturally occurring hormone， somatostatin. Lanreotide lowers the levels of hormones in the body such as GH （growth hormone） and IGF-1 （insulin-like growth factor-1） and inhibits some digestive hormones and intestinal secretions.
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序列:


溶解建议:
提供的兰乐肽产品为白色无菌冻干粉末.推荐使用无菌的18MΩ的超纯水来溶解，浓度不低于100ug/ml，便于后续稀释.

保存建议：
Lyophilized Lanreotide although stable at room temperature for 3 weeks， should be stored desiccated below -18℃. Upon reconstitution Lanreotide should be stored at 4℃ between 2-7 days and for future use below -18℃.For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.Please prevent freeze-thaw cycles.
其他简介：

  ProSpec是一家细胞因子蛋白及相关抗体生产和研发品Pai。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种Z多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。