EIF4EBP2抗体| EIF4EBP2 antibody_详细资料

产品信息

货号： PAab02723 抗体名： anti-EIF4EBP2 抗体,EIF4EBP2 抗体抗体英文名： anti-EIF4EBP2 antibody,EIF4EBP2 antibody 浓度： ≥95% as determined by SDS-PAGE 应用范围： ELISA,IHC,WB 宿主： Rabbit 供应商： LSM bio 数量： 50 保质期： 12 month 适应物种： Human, Mouse 克隆性：单克隆保存条件： PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.) 形态： liquid 亚型： IgG 免疫原： eukaryotic translation initiation factor 4E binding protein 2 规格： 100μg

EIF4EBP2抗体| EIF4EBP2 antibody
货号 PAab02723
蛋白别名
蛋白介绍
Repressor of translation initiation involved in synaptic plasticity, learning and memory formation (By similarity). Regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form of EIF4EBP2 competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation (PubMed:25533957). EIF4EBP2 is enriched in brain and acts as a regulator of synapse activity and neuronal stem cell renewal via its ability to repress translation initiation (By similarity). Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways (By similarity).

产品描述
anti-EIF4EBP2 antibody is a Rabbit Polyclonal antibody againstEIF4EBP2..
建议稀释比例

IHC
Immunohistochemistry of paraffin-embedded human prostate cancer using PAab02723(EIF4EBP2 antibody) at dilution of 1:100

Western blot
mouse testis tissue were subjected to SDS PAGE followed by western blot with PAab02723( EIF4EBP2 Antibody) at dilution of 1:300(本抗体仅供体外科研用途，不可用于临床诊断!)

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