Alpha B Crystallin抗体| Alpha B Crystallin antibody

货号  PAab00325

蛋白别名  Alpha B Crystallin antibody, Alpha crystallin B chain antibody, Alpha(B) crystallin antibody, CRYA2 antibody, CRYAB antibody, crystallin antibody, alpha B antibody, CTPP2 antibody, Heat shock protein beta 5 antibody, HSPB5 antibody, Rosenthal fiber component

蛋白介绍

Alpha B-crystallin, encoded by CRYAB gene, is multifunctional, serving as both a major structural protein in the lens and a small heat-shock protein in other tissues in mammals. Alpha B-crystallin may contribute to the transparency and refractive index of the lens. Single nucleotide polymorphisms (SNPs) in the promoter region of CRYAB gene have been associated with in multiple sclerosis. Mutations in the CRYAB gene cause distinct clinical phenotypes including isolated posterior polar cataract, myofibrillar myopathy, cardiomyopathy, or a multisystemic disorder combining all these features. Impairment of alpha-B crystallin dimerization may be relevant to the pathogenesis of these disorders.

产品描述

建议稀释比例

WB :1:500-1:5000;IHC:1:20-1:200;IP:1:200-1:2000

IHC

Immunohistochemistry of paraffin-embedded human eye using PAab00325(CRYAB antibody) at dilution of 1:100

Western blot

human heart tissue were subjected to SDS PAGE followed by western blot with PAab00325(CRYAB antibody) at dilution of 1:500(本抗体仅供体外科研用途，不可用于临床诊断!)

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